ENHANCE Study: Vytorin & Zetia Scandal

A message board to discuss personal experiences of Vytorin and its side effects.

ENHANCE Study: Vytorin & Zetia Scandal

Postby Darrell » Tue Jan 15, 2008 1:46 pm

"When Merck and Schering-Plough revealed Monday that the active ingredient in their top-selling cholesterol meds Zetia and Vytorin had flunked a clinical trial measuring its effect on artery plaque, they opened themselves up to a barrage of attacks."

"But in this study, LDL was cut 40% more for the people on Vytorin than those on the older drug Zocor, yet there was no benefit in terms of preventing the buildup of artery plaque."

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Postby vipergg22 » Tue Jan 15, 2008 8:41 pm

Just goes to show you these drug companies are pushing this stuff and it actually has less effect than they would like you to believe. I don't see where any of these statins have reduced heart disease , its just as prevalent as it was 20 years ago . I see in another pharm sponsored report that they think a lot of diabetics should be taking this stuff , yeah that will work great with all the side effects that these wonder drugs have . Diabetics have enough to deal with without dealing with statin side effects . You see this stuff is self propagating , they sell you statins which will then give muscle and nerve problems then they can sell more drugs to combat the side effects of those drugs , nice business to be in . At least the internet is around now so people in the know can look up this stuff.
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Postby Cat Mom2 » Wed Jan 16, 2008 7:56 pm

Go read this if you missed the CBS news tonight..


They sat on that report for 2 years and in the that time (after recieveing it) someone sold their stock for $28 million last spring, BEFORE the report was released.
Cat Mom2
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Postby vipergg22 » Fri Jan 18, 2008 8:20 pm

The truth is out , must read.

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Fun With Vytorin

Postby rickdperkins@verizon.net » Thu Jan 24, 2008 5:50 pm

Boy where do I start…..OK my name is Rick Perkins. I am 51 years old. About 4 years ago I after suffering what the Doctor was calling angina, I had my first heart cath done. This revealed two 90 percent blockages and one 70 percent blockage. Three stints were put in place. My Cardiologist did some extensive studies of my cholesterol, which by the way, was 295. The Doctor found that I was suffering from hereditary high cholesterol and put me on Lipitor and high blood pressure medicine, along with Plavix. After several months on Lipitor I suffered a cramp in my neck and jaw so severe that my Brother who is a Registered Nurse thought I was having a stroke. Due to this, the Doctor replaced Lipitor with Vytorin. My cholesterol dropped from 295 to 126. Over the next two years I still showed signs of angina with multiple incidents of chest pain. My doctor was concerned after showing weakness in my stress test and had another cath done. This cath showed clear. With no explanation of what was causing the pain. About a year later, here we go again, a third cath and still showed clear still no explanation of the cause of the pain. Another 8 months and this time I started to have strange experiences. I would be walking and just fall down. I would not know why. All I knew was I was walking and then I was picking myself up off the ground, sometimes with sprained body parts. So another stress test. This time the nuclear stress test showed blockage. Another cath was done by a different Doctor and this time as soon as the catheter was inserted, my heart went into full ventricular fibrillation and I soon stopped breathing on the table. The Doctor had to paddle me back. The Doctor said that I was relatively clear showing just about 30 percent blockage in some of my stints. However I was sent to Baylor Heart Hospital in Dallas to have an electro cardiology study done. This study showed nothing. So they implanted a reveal to monitor my heart rhythm. About two weeks after the implant I wind up in the hospital with pneumonia. While trying to determine what was causing the pneumonia, the Doctor found abnormal fluids. He stated that he thought my Gall Bladder was infected and caused the pneumonia. After 9 days in the Hospital I recovered and a Gall Bladder test was scheduled. My Gall Bladder showed only 28 percent of its normal function. The Doctor said that he thought this was due to sludge.
Surgery was scheduled and done. During the Surgery the Surgeon did not like the look of my Liver and did a Biopsy. The biopsy showed severe Liver damage with some necrosis.
In other words parts of my Liver are dead. Oh by the way, when the Gall Bladder was removed it was not full of sludge….JUST CRONICALLY SWOLEN. The Doctor then immediately ordered a full hepatic scan thinking I had hepatitis. The scan showed no viral hepatitis. It was during the time that I was awaiting the results of the lab test that the Vytorin scandal broke on the news, showing that they knew of the dangers and that it had no truly useful effect and had known so for two years before releasing the information…..so let me now take time to thank Merc and Schleberg Plough for their wonderful drug VYTORIN. I will let your imaginations tell you which finger I am holding up.

PS I am going cold turkey off Vytorin as we speak
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Postby Clouseau57 » Fri Feb 01, 2008 10:57 pm

Speaking of side effects - has anyone developed Irritable Bowel Syndrome, Ulcerative Colitis or Crohn's Disease after starting Zetia or Vytorin therapy?
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Postby JL » Sat Feb 09, 2008 2:26 am

Doctors sure know how to ruin someone's life, don't they? Document every detail of your experiences and be ready for payback time. Hopefully there's a good attorney out there who will take your case.
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