PN relief

A forum to discuss personal experiences of Neuropathy associated with statin drug use.

PN relief

Postby vipergg22 » Sat Dec 09, 2006 6:48 am

Anyone had any postive experiences on perpheral neuropathy using either alpha lipoic acid (have seen minor improvement) or acetyl L Carnitine ? ALC will be my next try at getting some relief from this wonderful statin induced disease .
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Postby Ray Holder » Sat Dec 09, 2006 2:49 pm

I have had no experience, but I would have thought Q10 to be a good thing to start with, Q10 deficiency is most likely to be the cause of nerve problems, carnitine is useful for muscle pain, where it is needed to transport waste products away from muscle

Ray Holder
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Postby catspajamas » Wed Feb 28, 2007 7:04 pm

I just read about coenzyme Q stated that it doesn't seem to improve nerve fact...may make it worse....muscle damage is another story....any comments on this?
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Postby cjbrooksjc » Wed Feb 28, 2007 9:10 pm

Catspjs: Here is an excerpt from a link I will provide below:

Pilot trial of high dosages of CoQ10 in patients with Parkinson's disease.
Exp Neurol. 2004 Aug;188(2):491-4.
The safety and tolerability of high dosages of coenzyme Q10 were studied in 17 patients with Parkinson's disease (PD) in an open label study. The subjects received an escalating dosage of coQ10 -- 1200, 1800, 2400, and 3000 mg/day with a stable dosage of vitamin E (alpha-tocopherol) 1200 IU/day. The plasma level of coQ10 was measured at each dosage. Thirteen of the subjects achieved the maximal dosage, and adverse events were typically considered to be unrelated to coQ10. The plasma level reached a plateau at the 2400 mg/day dosage and did not increase further at the 3000 mg/day dosage. Our data suggest that in future studies of CoQ10 in PD, a dosage of 2400 mg/day (with vitamin E/alpha-tocopherol 1200 IU/day) is an appropriate highest dosage to be studied.

This excerpt was found about five pages into this link. Sounds like you are concerned without reason. But, if you want to read more (and there is a LOT of it), go to:



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