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read this

Postby nanato3 » Wed Feb 13, 2008 9:43 am

Here is an article I read last night printed in Business Week magazine, a lengthy read but well worth it.

*http://www.businessweek.com/magazine/content/08_04/b4068052092994.htm?chan=magazine+channel_top+stories
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Postby cjbrooksjc » Wed Feb 13, 2008 1:04 pm

We've said it and said it here; now Business week has said it too! Following is an excerpt from the above article.

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Statin drugs work by bollixing up the production of a substance that gets turned into cholesterol in the liver, thus reducing levels in the blood. But the same substance turns out to be a building block for other key chemicals as well. Think of a toy factory in which the same plastic is fashioned into toy cars, trucks, and trains. Reducing production of the plastic cuts not only the output of toy cars (cholesterol) but also trucks and trains. In the body, these additional products are signaling molecules that tell genes to turn on or off, causing both side effects and benefits.

Liao has charted some of these biochemical pathways. His recent work shows that one of the trucks, as it were—a molecule called Rho-kinase—is key. By reducing the amount of this enzyme, statins dial back damaging inflammation in arteries. When Liao knocks down the level of Rho-kinase in rats, they don't get heart disease. "Cholesterol lowering is not the reason for the benefit of statins," he concludes.

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What is not said is that there are other, even more effective anti-inflammatories available; so, why use Statins at all? It's the 'trucks and trains' issue that pertains to us and spelled: CoQ10, Dolichols, and HEME.

"MISGUIDED CHILDREN OF UNWED MOTHERS!"
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